Highly sensitive real-time PCR for the detection of EGFR mutations in lung adenocarcinoma. Is it worth it?

Rodon Natalia1, Roman Ruth1, Verdu Montse1,3, Garcia Beatriz1, Pujol Merce1 and Puig Xavier1,2,3.

1BIOPAT.Biopatologia Molecular, SL, Grup Assistencia, Barcelona, Spain; 2Hospital de Barcelona, SCIAS, Grup Assistencia, Barcelona, Spain; 3Histopat Laboratoris, Barcelona, Spain.

Background: Mutations involving the epidermal growth factor receptor (EGFR) correlate with responsiveness to tyrosine kinase inhibitors (TKIs), which significantly improves patient survival in lung adenocarcinoma (AC). These mutations are described […]

2012-03-14T23:31:31+00:00

ERG Expression in 175 Prostatic Carcinomas and 270 Carcinomas from Different Primary Sites

Verdu Montse1,3, Roman Ruth1, Calvo Miquel4, Rodon Natalia1, Garcia Beatriz1, Pujol Merce1 and Puig Xavier1,2,3.

1BIOPAT.Biopatologia Molecular, SL, Grup Assistencia, Barcelona, Spain; 2Hospital de Barcelona, SCIAS, Grup Assistencia, Barcelona, Spain; 3Histopat Laboratoris, Barcelona, Spain; 4Universitat de Barcelona(UB), Statistics Dpt., Barcelona, Spain;

Background: ERG gene rearrangement, detected by FISH or RT-PCR, has been identified as a highly specific alteration, present in 40-50% of prostate […]

2012-03-14T23:29:15+00:00

Utilidad del estudio de alteraciones cromosómicas en el diagnóstico y seguimiento de pacientes con carcinoma urotelial

Beatriz García-Peláez1, Ruth Román1, Isabel Trias4, Naim Hannaoui5, Josep M. Banús5, Montse Verdú1, 3, Natàlia Rodon1, Marta Gonzalez1, Mercè Pujol1, Myriam Górriz3, Carme Pubill3 y Xavier Puig1,2,3.

1 BIOPAT. Biopatología Molecular SL, Grup Assistència. 2 Hospital de Barcelona-SCIAS, Grup Assistència. 3 Histopat Laboratoris. 4 Hospital Plató. 5 Institut Català d’ Urologia i Nefrologia SL (ICUN) Barcelona.

Introducción: […]

2011-05-26T15:25:32+00:00

Clinicopathological and molecular characterization of colorectal micropapillary carcinoma

Montse Verdú1,2, Ruth Román1, Miquel Calvo3, Natàlia Rodón1, Beatriz García1, Marta González1, August Vidal1,2, and Xavier Puig1,2,4.

1BIOPAT. Biopatologia Molecular, SL, Grup Assistencia, Barcelona, Spain; 2 Histopat Laboratoris, Barcelona, Spain; 3Statistics Department, Universitat de Barcelona, Barcelona, Spain and 4Hospital de Barcelona, SCIAS, Grup Assistencia, Barcelona, Spain.

Abstract

Invasive micropapillary carcinoma is associated with frequent lymph node metastasis and […]

2011-05-06T13:52:25+00:00

Prospective study of HER2 status in 1386 invasive breast carcinomas. The impact of the ASCO/CAP 2007 guidelines.

Montse Verdú1,2, Marta González1, Ruth Roman1, Natalia Rodón1, Carme Pubill2, Begoña Martínez1,2, Myriam Gorriz2, Beatriz Garcia-Pelaez1, Miquel Calvo4 and Xavier Puig1,2,3.

1BIOPAT. Biopatologia Molecular, SL, Grup Assistència; 2Histopat Laboratoris;  3Hospital de Barcelona SCIAS, Grup Assistència and 4Statistics Department, Universitat de Barcelona. Barcelona, Spain.

Background: The introduction of the ASCO/CAP guidelines in 2007 followed the need to unify methodologies used […]

2011-03-11T18:29:48+00:00