Genetic alterations of the epidermal growth factor receptor pathway in a series of non-small cell lung cancer characterized by morphology and immunophenotype

Verdú M,1 Colomer A,1 Erill N,1 Roman R,2 Górriz M, 1,2 Ibáñez R,1 Cordon-Cardo C,1 Puig X.1,2

1HISTOPAT Laboratoris, Barcelona, Catalonia, Spain & 2BIOPAT. Biopatologia Molecular, Grup Assistència.

Background: Non-small cell lung cancer (NSCLC) is classified in two main categories: adenocarcinoma (AC), which includes bronchioloalveolar carcinoma (BAC), and squamous cell carcinoma (SCC). Activating mutations and increased copy […]

2006-09-23T17:54:01+00:00

A population study on the UGT1A1*28 variant associated to Irinotecan tolerance

Roman R,1 Colomer A,1 Erill N,1 Verdú M,2 Ibáñez R,1 Cordon-Cardo C,1 Puig X.1,2

1BIOPAT. Biopatologia Molecular, Grup Assistència & 2HISTOPAT Laboratoris, Barcelona, Catalonia, Spain.

Background: Irinotecan (CPT-11) is currently used as first- or second-line treatment for colorectal cancer, either alone or in combination with 5-fluorouracil based regimens. UDP-glucuronosyltransferase 1A1 (UGT1A1) catalyzes the inactivation of SN-38, the […]

2006-09-23T17:11:42+00:00

Epidermal growth factor receptor in non small cell lung cancer: Gene copy number and mutational study

Colomer A1, Erill N1, Verdú M2, Román R 1, Górriz M2, Ibáñez R1, Menoyo A1, Cordon-Cardo C3, Puig X 1,2.

1BIOPAT, Grup Assistència, 2HISTOPAT Laboratoris, Barcelona, Spain; and 3Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York, United States.

Background: Activating mutations of the EGFR gene were identified in tumors from patients with non small cell […]

2006-02-23T17:52:21+00:00

Carcinoma de pulmón de células no pequeñas: caracterización inmunohistoquímica y estudio molecular del gen del receptor de EGF

N Erill1, A Colomer1, M Verdú2, R Román1, A Menoyo1, Carlos Cordón-Cardó1,2,3, Xavier Puig1,2.

1 BIOPAT. Biopatologia Molecular.  Grup Assistència. Barcelona. 2 Histopat laboratoris, Barcelona. 3 Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York. 

Texto completo

Póster presentado en:

XXII Congreso de la Sociedad Española de Anatomía Patológica 2005

2005-09-01T01:25:02+00:00

Estudio mutacional de BRAF y KRAS en cáncer colorrectal: carcinoma esporádico versus síndrome familiar no asociado a poliposis

A Colomer1, N Erill1, A Vidal1, 2, M Verdú2, R Román1, C. Cordón3, X Puig1,2.

1 BIOPAT. Biopatologia Molecular.  Grup Assistència. Barcelona. 2 Histopat laboratoris, Barcelona. 3 Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York. 

Texto compelto

Póster presentado en:

X Congreso Nacional de la Sociedad Española de […]

2005-09-01T01:17:23+00:00